31917969 Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs.

Seaman MS, Bilska M, Ghantous F, Eaton A, LaBranche CC, Greene K, Gao H, Weiner JA, Ackerman ME, Garber DA, Rosenberg YJ, Sarzotti-Kelsoe M, Montefiori DC.
J Immunol Methods. 2020 Jan 6:112736. doi: 10.1016/j.jim.2020.112736.
PMID: 31917969

31841557 IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody.

Richardson SI, Lambson BE, Crowley AR, Bashirova A, Scheepers C, Garrett N, Abdool Karim S, Mkhize NN, Carrington M, Ackerman ME, Moore PL, Morris L.
PLoS Pathog. 2019 Dec 16;15(12):e1008064. doi: 10.1371/journal.ppat.1008064
PMID: 31841557

31669096IgG Fc glycosylation as an axis of humoral immunity in childhood.

Cheng HD, Tirosh I, de Haan N, Stöckmann H, Adamczyk B, McManus CA, O'Flaherty R, Greville G, Saldova R, Bonilla FA, Notarangelo LD, Driessen GJ, Holm IA, Rudd PM, Wuhrer M, Ackerman ME, Nigrovic PA.
J Allergy Clin Immunol. 2019 Oct 24. pii: S0091-6749(19)31364-8. doi: 10.1016/j.jaci.2019.10.012.
PMID: 31669096

31581292Longitudinal antibody responses in people who inject drugs infected with similar HIV strains.

Redd AD, Doria-Rose NA, Weiner JA, Nason M, Seivers M, Schmidt SD, Laeyendecker O, Martens C, Bruno D, Keele BF, Raju N, Georgiev IS, Lamers SL, Astemborski J, Kirk GD, Mascola JR, Ackerman ME, Mehta SH, Quinn TC.
J Infect Dis. 2019 Oct 4. pii: jiz503. doi: 10.1093/infdis/jiz503. [Epub ahead of print]
PMID: 31581292

31543993Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden.

Brickley EB, Connor RI, Wieland-Alter WF, Collett MS, Hartford M, Van Der Avoort H, Boesch AW, Weiner JA, Ackerman ME, McKinlay MA, Arita M, Bandyopadhyay AS, Modlin JF, Wright PF.
BMJ Glob Health. 2019 Aug 28;4(4):e001613. doi: 10.1136/bmjgh-2019-001613. eCollection 2019.
PMID: 31543993

31393868Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study.

Cohen YZ, Butler AL, Millard K, Witmer-Pack M, Levin R, Unson-O'Brien C, Patel R, Shimeliovich I, Lorenzi JCC, Horowitz J, Walsh SR, Lin S, Weiner JA, Tse A, Sato A, Bennett C, Mayer B, Seaton KE, Yates NL, Baden LR, deCamp AC, Ackerman ME, Seaman MS, Tomaras GD, Nussenzweig MC, Caskey M.
PLoS One. 2019 Aug 8;14(8):e0219142. doi: 10.1371/journal.pone.0219142. eCollection 2019.
PMID: 31393868

31204101Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women.

Martinez DR, Fong Y, Li SH, Yang F, Jennewein MF, Weiner JA, Harrell EA, Mangold JF, Goswami R, Seage GR 3rd, Alter G, Ackerman ME, Peng X, Fouda GG, Permar SR.
Cell. 2019 Jun 11. pii: S0092-8674(19)30617-8. doi: 10.1016/j.cell.2019.05.046.

31134085Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1

Lewis GK, Ackerman ME, Scarlatti G, Moog C, Robert-Guroff M, Kent SJ, Overbaugh J, Reeves RK, Ferrari G, Thyagarajan B.
Front Immunol. 2019 May 10;10:1025. doi: 10.3389/fimmu.2019.01025. eCollection 2019. Review.

31048360Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection.

Pittala S, Bagley K, Schwartz JA, Brown EP, Weiner JA, Prado IJ, Zhang W, Xu R, Ota-Setlik A, Pal R, Shen X, Beck C, Ferrari G, Lewis GK, LaBranche CC, Montefiori DC, Tomaras GD, Alter G, Roederer M, Fouts TR, Ackerman ME, Bailey-Kellogg C.
Mol Syst Biol. 2019 May 2;15(5):e8747. doi: 10.15252/msb.20188747.

31033729Systems serology for decoding infection and vaccine-induced antibody responses to HIV-1.

Pittala S, Morrison KS, Ackerman ME.
Curr Opin HIV AIDS. 2019 Apr 24. doi: 10.1097/COH.0000000000000558. [Epub ahead of print]

30971454Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity.

Patel CD, Backes IM, Taylor SA, Jiang Y, Marchant A, Pesola JM, Coen DM, Knipe DM, Ackerman ME, Leib DA.
Sci Transl Med. 2019 Apr 10;11(487). pii: eaau6039. doi: 10.1126/scitranslmed.aau6039.

31024542Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function.

Crowley AR, Ackerman ME.
Front Immunol. 2019 Apr 8;10:697. doi: 10.3389/fimmu.2019.00697. eCollection 2019. Review.

30376086Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chilean Infants.

Brickley EB, Wieland-Alter W, Connor RI, Ackerman ME, Boesch AW, Arita M, Weldon WC, O'Ryan MG, Bandyopadhyay AS, Wright PF.
Clin Infect Dis. 2018 Oct 30;67(suppl_1):S42-S50. doi: 10.1093/cid/ciy603.

30232424Evidence that CD32a does not mark the HIV-1 latent reservoir.

Osuna CE, Lim SY, Kublin JL, Apps R, Chen E, Mota TM, Huang SH, Ren Y, Bachtel ND, Tsibris AM, Ackerman ME, Jones RB, Nixon DF, Whitney JB.
Nature. 2018 Sep;561(7723):E20-E28. doi: 10.1038/s41586-018-0495-2. Epub 2018 Sep 19. No abstract available. Erratum in: Nature. 2018 Oct 12.

30177821Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.

Ackerman ME, Das J, Pittala S, Broge T, Linde C, Suscovich TJ, Brown EP, Bradley T, Natarajan H, Lin S, Sassic JK, O'Keefe S, Mehta N, Goodman D, Sips M, Weiner JA, Tomaras GD, Haynes BF, Lauffenburger DA, Bailey-Kellogg C, Roederer M, Alter G.
Nat Med. 2018 Sep 3. doi: 10.1038/s41591-018-0161-0. [Epub ahead of print]

30161231Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?

Martinez DR, Fouda GG, Peng X, Ackerman ME, Permar SR.
PLoS Pathog. 2018 Aug 30;14(8):e1007161. doi: 10.1371/journal.ppat.1007161. eCollection 2018 Aug.

30120121 Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.

Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G.
Sci Immunol. 2018 Aug 17;3(26). pii: eaat7796. doi: 10.1126/sciimmunol.aat7796.

30021899Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques.

Miller-Novak LK, Das J, Musich TA, Demberg T, Weiner JA, Venzon DJ, Mohanram V, Vargas-Inchaustegui DA, Tuero I, Ackerman ME, Alter G, Robert-Guroff M.
J Virol. 2018 Jul 18. pii: JVI.00721-18. doi: 10.1128/JVI.00721-18.

29897567Towards conformational fidelity of a quaternary HIV-1 epitope: computational design and directed evolution of a minimal V1V2 antigen.

Lai JI, Verma D, Bailey-Kellogg C, Ackerman ME.
Protein Eng Des Sel. 2018 Jun 12. doi: 10.1093/protein/gzy010. [Epub ahead of print]

29630668HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

Richardson SI, Chung AW, Natarajan H, Mabvakure B, Mkhize NN, Garrett N, Abdool Karim S, Moore PL, Ackerman ME, Alter G, Morris L.
PLoS Pathog. 2018 Apr 9;14(4):e1006987. doi: 10.1371/journal.ppat.1006987. [Epub ahead of print]

29453518Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression..

Gacerez AT, Hua CK, Ackerman ME, Sentman CL.
Cancer Immunol Immunother. 2018 Feb 16. doi: 10.1007/s00262-018-2124-1. [Epub ahead of print]

29581149High-resolution definition of humoral immune response correlates of effective immunity against HIV.

Alter G, Dowell KG, Brown EP, Suscovich TJ, Mikhailova A, Mahan AE, Walker BD, Nimmerjahn F, Bailey-Kellogg C, Ackerman ME.
Mol Syst Biol. 2018 Mar 26;14(3):e7881. doi: 10.15252/msb.20177881.

29515029Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site.

Cheng HD, Grimm SK, Gilman MS, Gwom LC, Sok D, Sundling C, Donofrio G, Hedestam GBK, Bonsignori M, Haynes BF, Lahey TP, Maro I, von Reyn CF, Gorny MK, Zolla-Pazner S, Walker BD, Alter G, Burton DR, Robb ML, Krebs SJ, Seaman MS, Bailey-Kellogg C, Ackerman ME.
JCI Insight. 2018 Mar 8;3(5). pii: 97018. doi: 10.1172/jci.insight.97018. [Epub ahead of print]

29395167Optimization and qualification of an Fc Array assay for assessments of antibodies against HIV-1/SIV.

Brown EP, Weiner JA, Lin S, Natarajan H, Normandin E, Barouch DH, Alter G, Sarzotti-Kelsoe M, Ackerman ME.
J Immunol Methods. 2018 Jan 29. pii: S0022-1759(17)30302-2. doi: 10.1016/j.jim.2018.01.013. [Epub ahead of print]

29315477 Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands.

Boesch AW, Kappel JH, Mahan AE, Chu TH, Crowley AR, Osei-Owusu NY, Alter G, Ackerman ME.
Biotechnol Bioeng. 2018 Jan 8. doi: 10.1002/bit.26545. [Epub ahead of print]

29304199Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine.

Brickley EB, Strauch CB, Wieland-Alter WF, Connor RI, Lin S, Weiner JA, Ackerman ME, Arita M, Oberste MS, Weldon WC, Sáez-Llorens X, Bandyopadhyay AS, Wright PF.
J Infect Dis. 2018 Jan 17;217(3):371-380. doi: 10.1093/infdis/jix556.

29309656Mucosal Immunity: The Forgotten Arm of the Immune System: Synopsis of the Pediatric Infectious Disease Society's 2017 Stanley A. Plotkin Lecture in Vaccinology.

Wright PF, Ackerman ME, Brickley EB.
J Pediatric Infect Dis Soc. 2017 Dec 22. doi: 10.1093/jpids/pix102. [Epub ahead of print]


29234320Increasing the Clinical Potential and Applications of Anti-HIV Antibodies.

Hua CK, Ackerman ME.
Front Immunol. 2017 Nov 28;8:1655. doi: 10.3389/fimmu.2017.01655. eCollection 2017. Review.



29199956Computationally-driven identification of antibody epitopes.

Hua CK, Gacerez AT, Sentman CL, Ackerman ME, Choi Y, Bailey-Kellogg C.
Elife. 2017 Dec 4;6. pii: e29023. doi: 10.7554/eLife.29023.



2017011411Innate transcriptional effects by adjuvants on the magnitude, quality, and durability2017 of HIV envelope responses in NHP

Francica JR, Zak DE, Linde C, Siena E, Johnson C, Juraski M, Yates NL, Gunn B, De Gregorio E, Flynn BJ, Valiante NM, Malyala P, Barnett SW, Sarkar P, Singh M, Jain S, Ackerman M, Alam M, Ferrari G, Tomaras GD, O'Hagan DT, Aderem A, Alter G, Seder RA.
Blood Advances. 2017 1:2329-2342; doi:


29083319HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells.

Veenhuis RT, Freeman ZT, Korleski J, Cohen LK, Massaccesi G, Tomasi A, Boesch AW, Ackerman ME, Margolick JB, Blankson JN, Chattergoon MA, Cox AL.
J Clin Invest. 2017 Oct 30. pii: 95375. doi: 10.1172/JCI95375. [Epub ahead of print]


29040754Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6.

Hua CK, Gacerez AT, Sentman CL, Ackerman ME.
Protein Eng Des Sel. 2017 Oct 11:1-9. doi: 10.1093/protein/gzx051. [Epub ahead of print]

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28973482High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis.

Cheng HD, Stöckmann H, Adamczyk B, McManus CA, Ercan A, Holm IA, Rudd PM, Ackerman ME*, Nigrovic PA*.
Glycobiology. 2017 Sep 14. doi: 10.1093/glycob/cwx082. [Epub ahead of print]

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28933630Going Native: direct high throughput screening of secreted full-length IgG antibodies against cell membrane proteins.

Fang Y, Chu TH, Ackerman ME, Griswold KE.
MAbs. 2017 Sep 21:0. doi: 10.1080/19420862.2017.1381812. [Epub ahead of print]

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28593989Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.

Bradley T, Pollara J, Santra S, Vandergrift N, Pittala S, Bailey-Kellogg C, Shen X, Parks R, Goodman D, Eaton A, Balachandran H, Mach LV, Saunders KO, Weiner JA, Scearce R, Sutherland LL, Phogat S, Tartaglia J, Reed SG, Hu SL, Theis JF, Pinter A, Montefiori DC, Kepler TB, Peachman KK, Rao M, Michael NL, Suscovich TJ, Alter G, Ackerman ME, Moody MA, Liao HX, Tomaras G, Ferrari G, Korber BT, Haynes BF.
Nat Commun. 2017 Jun 8;8:15711. doi: 10.1038/ncomms15711.

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28235027Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

Easterhoff D, Moody MA, Fera D, Cheng H, Ackerman M, Wiehe K, Saunders KO, Pollara J, Vandergrift N, Parks R, Kim J, Michael NL, O'Connell RJ, Excler JL, Robb ML, Vasan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Sinangil F, Tartaglia J, Phogat S, Kepler TB, Alam SM, Liao HX, Ferrari G, Seaman MS, Montefiori DC, Tomaras GD, Harrison SC, Haynes BF.
PLoS Pathog. 2017 Feb 24;13(2):e1006182. doi: 10.1371/journal.ppat.1006182. [Epub ahead of print]

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28133810Systems serology for evaluation of HIV vaccine trials.

Ackerman ME, Barouch DH, Alter G.
Immunol Rev. 2017 Jan;275(1):262-270. doi: 10.1111/imr.12503. Review.

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28133810Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles.

Brown EP, Dowell KG, Boesch AW, Normandin E, Mahan AE, Chu T, Barouch DH, Bailey-Kellogg C, Alter G, Ackerman ME.
J Immunol Methods. 2017 Feb 2. pii: S0022-1759(16)30386-6. doi: 10.1016/j.jim.2017.01.010.

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graphicIgG Fc variant cross-reactivity between human and rhesus macaque FcγRs.

Boesch AW, Miles AR, Chan YN, Osei-Owusu NY, Ackerman ME.
MAbs. 2017 Jan 5:0. doi: 10.1080/19420862.2016.1274845.

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graphicBiophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.

Boesch AW, Osei-Owusu NY, Crowley AR, Chu TH, Chan YN, Weiner JA, Bharadwaj P, Hards R, Adamo ME, Gerber SA, Cocklin SL, Schmitz JE, Miles AR, Eckman JW, Belli AJ, Reimann KA, Ackerman ME.
Front Immunol. 2016 Dec 13;7:589. doi: 10.3389/fimmu.2016.00589.

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graphicDiversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects.

Huang Y, Ferrari G, Alter G, Forthal DN, Kappes JC, Lewis GK, Love JC, Borate B, Harris L, Greene K, Gao H, Phan TB, Landucci G, Goods BA, Dowell KG, Cheng HD, Bailey-Kellogg C, Montefiori DC, Ackerman ME.
J Immunol. 2016 Dec 15;197(12):4603-4612.


graphicVaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants.

Wright PF, Connor RI, Wieland-Alter WF, Hoen AG, Boesch AW, Ackerman ME, Oberste MS, Gast C, Brickley EB, Asturias EJ, Rüttimann R, Bandyopadhyay AS.
Lancet Infect Dis. 2016 Sep 13. pii: S1473-3099(16)30169-4. doi: 10.1016/S1473-3099(16)30169-4.

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graphicDendritic cells from the human female reproductive tract rapidly capture and respond to HIV.

Rodriguez-Garcia M, Shen Z, Barr FD, Boesch AW, Ackerman ME, Kappes JC, Ochsenbauer C, Wira CR.
Mucosal Immunol. 2016 Aug 31. doi: 10.1038/mi.2016.72.

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graphicIgG Binding Characteristics of Rhesus Macaque FcγR.

Chan YN, Boesch AW, Osei-Owusu NY, Emileh A, Crowley AR, Cocklin SL, Finstad SL, Linde CH, Howell RA, Zentner I, Cocklin S, Miles AR, Eckman JW, Alter G, Schmitz JE, Ackerman ME.
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graphic Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine.

Wright PF, Hoen AG, Ilyushina NA, Brown EP, Ackerman ME, Wieland-Alter W, Connor RI, Jegaskanda S, Rosenberg-Hasson Y, Haynes BC, Luke CJ, Subbarao K, Treanor JJ.
Open Forum Infect Dis. 2016 May 23;3(2):ofw108. doi: 10.1093/ofid/ofw108. eCollection 2016 Apr.

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graphic Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.

Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, Ackerman ME, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, Pegu P, Montefiori DC, Foulds K, Quinn DS, Donaldson M, Liang F, Loré K, Roederer M, Koup RA, McDermott A, Ma ZM, Miller CJ, Phan TB, Forthal DN, Blackburn M, Caccuri F, Bissa M, Ferrari G, Kalyanaraman V, Ferrari MG, Thompson D, Robert-Guroff M, Ratto-Kim S, Kim JH, Michael NL, Phogat S, Barnett SW, Tartaglia J, Venzon D, Stablein DM, Alter G, Sekaly RP, Franchini G.
Nat Med. 2016 May 30. doi: 10.1038/nm.4105. [Epub ahead of print]

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Sips M, Krykbaeva M, Diefenbach TJ, Ghebremichael M, Bowman BA, Dugast AS, Boesch AW, Streeck H, Kwon DS, Ackerman ME, Suscovich TJ, Brouckaert P, Schacker TW, Alter G.
Mucosal Immunol. 2016 Feb 17. doi: 10.1038/mi.2016.12. [Epub ahead of print]

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graphic Engineering broadly neutralizing antibodies for HIV prevention and therapy.

Hua CK, Ackerman ME. Adv Drug Deliv Rev. 2016 Jan 28. pii: S0169-409X(16)30030-8. doi: 10.1016/j.addr.2016.01.013. [Epub ahead of print] Review.

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Ackerman ME, Mikhailova A, Brown EP, Dowell KG, Walker BD, Bailey-Kellogg C, Suscovich TJ, Alter G. PLoS Pathog. 2016 Jan 8;12(1):e1005315. doi: 10.1371/journal.ppat.1005315.
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Chung AW, Kumar MP, Arnold KB, Yu WH, Schoen MK, Dunphy LJ, Suscovich TJ, Frahm N, Linde C, Mahan AE, Hoffner M, Streeck H, Ackerman ME, McElrath MJ, Schuitemaker H, Pau MG, Baden LR, Kim JH, Michael NL, Barouch DH, Lauffenburger DA, Alter G.
Cell. 2015 Nov 5;163(4):988-98. doi: 10.1016/j.cell.2015.10.027.

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Immunol Rev. 2015 Nov;268(1):296-310. doi: 10.1111/imr.12339. Review.

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Storcksdieck Genannt Bonsmann M, Niezold T, Temchura V, Pissani F, Ehrhardt K, Brown EP, Osei-Owusu NY, Hannaman D, Hengel H, Ackerman ME, Streeck H, Nabi G, Tenbusch M, Überla K.
J Immunol. 2015 Oct 14. pii: 1501377. [Epub ahead of print]

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graphicLambda light chain bias associated with enhanced binding and function of anti-HIV Env glycoprotein antibodies.

Sajadi MM, Farshidpour M, Brown EP, Ouyang X, Seaman MS, Pazgier M, Ackerman ME, Robinson H, Tomaras G, Parsons MS, Charurat M, DeVico AL, Redfield RR, Lewis GK.
J Infect Dis. 2015 Sep 7. pii: jiv448. [Epub ahead of print]

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Choi Y, Hua C, Sentman CL, Ackerman ME, Bailey-Kellogg C.
MAbs. 2015 Aug 7:0. [Epub ahead of print]

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Barouch DH, Alter G, Broge T, Linde C, Ackerman MEBrown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, Seaman MS, Lavine CL, Perry JR, Li W, Colantonio AD, Lewis MG, Chen B, Wenschuh H, Reimer U, Piatak M, Lifson JD, Handley SA, Virgin HW, Koutsoukos M, Lorin C, Voss G, Weijtens M, Pau MG, Schuitemaker H..
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Brown EP, Normandin E, Osei-Owusu NY, Mahan AE, Chan YN, Lai JI, Vaccari M, Rao M, Franchini G, Alter G, Ackerman ME.
J Immunol Methods. 2015 Jun 12. pii: S0022-1759(15)30007-7. doi: 10.1016/j.jim.2015.06.005. [Epub ahead of print]

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Choi I, Chung AW, Suscovich TJ, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kaewkungwal J, O'Connell RJ, Francis D, Robb ML, Michael NL, Kim JH, Alter G, Ackerman ME, Bailey-Kellogg C.
PLoS Comput Biol. 2015 Apr 13;11(4):e1004185. doi: 10.1371/journal.pcbi.1004185. eCollection 2015 Apr.

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Grimm SK, Battles MB, Ackerman ME.
PLoS One. 2015 Feb 17;10(2):e0117227. doi: 10.1371/journal.pone.0117227. eCollection 2015.
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Mahan AE, Tedesco J, Dionne K, Baruah K, Cheng HD, De Jager PL, Barouch DH, Suscovich T, Ackerman M, Cripsin M, Alter G.
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graphicLive Attenuated and Inactivated Influenza Vaccines in Children.

Ilyushina NA, Haynes BC, Hoen AG, Khalenkov AM, Housman ML, Brown EP, Ackerman ME, Treanor JJ, Luke CJ, Subbarao K, Wright PF.
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PLoS One 2014Lack of Protection following Passive Transfer of Polyclonal Highly Functional Low-Dose Non-Neutralizing Antibodies.

Dugast AS, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G.
PLoS One. 2014 May 12;9(5):e97229. doi: 10.1371/journal.pone.0097229. eCollection 2014.
PMID: 24820481 [PubMed - in process]

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Sci Transl Med 2014Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines.

Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, Nitayaphan S, de Souza MS, Kaewkungwal J, Pitisuttithum P, Francis D, Michael NL, Kim JH, Bailey-Kellogg C, Ackerman ME, Alter G.
Sci Transl Med. 2014 Mar 19;6(228):228ra38. doi: 10.1126/scitranslmed.3007736.
PMID: 24648341 [PubMed - in process]

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J Clin Invest. 2014An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

Bonsignori M, Wiehe K, Grimm SK, Lynch R, Yang G, Kozink DM, Perrin F, Cooper AJ, Hwang KK, Chen X, Liu M, McKee K, Parks RJ, Eudailey J, Wang M, Clowse M, Criscione-Schreiber LG, Moody MA, Ackerman ME, Boyd SD, Gao F, Kelsoe G, Verkoczy L, Tomaras GD, Liao HX, Kepler TB, Montefiori DC, Mascola JR, Haynes BF.
J Clin Invest. 2014 Mar 10. pii: 73441. doi: 10.1172/JCI73441.
[Epub ahead of print]
PMID: 24614107 [PubMed - as supplied by publisher]

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J Infect Dis 2014Intestinal Immunity Is a Determinant of Clearance of Poliovirus After Oral Vaccination.

Wright PF, Wieland-Alter W, Ilyushina NA, Hoen AG, Arita M, Boesch AW, Ackerman ME, van der Avoort H, Steven Oberste M, Pallansch MA, Burton AH, Jaffar MA, Sutter RW.
J Infect Dis. 2014 Jan 23. [Epub ahead of print]
PMID: 24459191 [PubMed - as supplied by publisher]

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J Virol 2013Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers.

Lai JI, Licht AF, Dugast AS, Suscovich T, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME.
J Virol. 2013 Dec 18. [Epub ahead of print]
PMID: 24352471 [PubMed - as supplied by publisher]

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Curr HIV Res.Opportunities to Exploit Non-Neutralizing HIV-Specific Antibody Activity

Ackerman ME, Alter G.
Curr HIV Res. 2013 Nov 4. [Epub ahead of print]
PMID: 24191934 [PubMed - as supplied by publisher]

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Academic PressAntibody Fc: Linking Adaptive and Innate Immunity

Margaret Ackerman, Falk Nimmerjahn (Editors)
Academic Press, Elsevier, 2013 Oct 4. ISBN-10: 0123948029 | ISBN-13: 978-0123948021

Journal Immunology MethodsA Multiplexed Assay to Detect Antimicrobial Peptides in Biological Fluids and Cell Secretions

Boesch AW, Zhao Y, Landman AS, Garcia MR, Fahey JV, Wira CR, Ackerman ME.
J Immunol Methods. 2013 Sep 10. doi:pii: S0022-1759(13)00241-X. 10.1016/j.jim.2013.09.001. [Epub ahead of print]

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New England Journal of MedicineMapping the journey to an HIV vaccine

Ackerman M, Alter G.
N Engl J Med. 2013 Jul 25;369(4):389-91. doi: 10.1056/NEJMcibr1304437. No abstract available.
PMID: 23883384 [PubMed - in process]

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J Clin InvestNatural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G.
J Clin Invest. 2013 Apr 8. doi:pii: 65708. 10.1172/JCI65708. [Epub ahead of print]
PMID: 23563315 [PubMed - as supplied by publisher]

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J Virol 2013Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b

Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G.
J Virol. 2013 Mar 6. [Epub ahead of print]
PMID: 23468489 [PubMed - as supplied by publisher]

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Curr Opin Biotechnol 2013Vaccine design: emerging concepts and renewed optimism

Grimm SK, Ackerman ME.
Curr Opin Biotechnol. 2013 Mar 6. doi:pii: S0958-1669(13)00029-3. 10.1016/j.copbio.2013.02.015. [Epub ahead of print]
PMID: 23474232 [PubMed - as supplied by publisher]

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Biotechnol Prog 2013Separation of nonfucosylated antibodies with immobilized FcγRIII receptors

Bolton GR, Ackerman ME, Boesch AW.
Biotechnol Prog. 2013 Mar 6. doi: 10.1021/btpr.1717. [Epub ahead of print]
PMID: 23463721 [PubMed - as supplied by publisher]

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J Immunol Methods. 2013 Jan 24What mAbs Tell Us about Shapes: Multiple Roads Lead to Rome

Alter G, Ackerman ME.
Immunity. 2013 Jan 24;38(1):8-9.
doi: 10.1016/j.immuni.2013.01.003. PMID: 23352219 [Epub ahead of print]

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J Immunol Methods. 2012 Sep 27High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples

Brown EP, Licht AF, Dugast AS, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME.
J Immunol Methods. 2012 Sep 27.
pii: S0022-1759(12)00289-X. doi: 10.1016/j.jim.2012.09.007. [Epub ahead of print]

Annu Rev Med. 2012 FebEmerging Concepts on the Role of Innate Immunity in the Prevention and Control of HIV Infection

Ackerman ME, Dugast AS, Alter G.
Annu Rev Med. 2012 Feb 18;63:113-30. Epub 2011 Nov 8.
PMID: 22077718 [PubMed - in process]

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J Vis Exp. 2011 NovDetermining the phagocytic activity of clinical antibody samples

McAndrew EG, Dugast AS, Licht AF, Eusebio JR, Alter G, Ackerman ME.
J Vis Exp. 2011 Nov 30;(57). pii: 3588. doi: 10.3791/3588.
PMID: 22143444 [PubMed - in process]

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Protein Eng Des Sel. 2011 NovExploiting bias in a non-immune human antibody library to predict antigenicity

Ackerman ME, Lai JI, Pastan I, Wittrup KD.
Protein Eng Des Sel. 2011 Nov;24(11):845-53. Epub 2011 Sep 9.
PMID: 21908549 [PubMed - in process]

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Virology. 2011 Jul 5

Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals

Dugast AS, Tonelli A, Berger CT, Ackerman ME, Sciaranghella G, Liu Q, Sips M, Toth I, Piechocka-Trocha A, Ghebremichael M, Alter G.
Virology. 2011 Jul 5;415(2):160-7. Epub 2011 May 12.
PMID: 21565376 [PubMed - indexed for MEDLINE]

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PLoS One. 2011 AprProtein-protein fusion catalyzed by sortase A

Levary DA, Parthasarathy R, Boder ET, Ackerman ME.
PLoS One. 2011 Apr 6;6(4):e18342.
PMID: 21494692 [PubMed - indexed for MEDLINE] Free PMC Article

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J Immunol Methods. 2011 Mar A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G.
J Immunol Methods. 2011 Mar 7;366(1-2):8-19. Epub 2010 Dec 27.
PMID: 21192942 [PubMed - indexed for MEDLINE]

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PLoS One. 2011 FebGenetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity

Lamppa JW, Ackerman ME, Lai JI, Scanlon TC, Griswold KE.
PLoS One. 2011 Feb 14;6(2):e17042.
PMID: 21340021 [PubMed - indexed for MEDLINE] Free PMC Article

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J Mol Biol. 2010 AugStability and CDR composition biases enrich binder functionality landscapes

Hackel BJ, Ackerman ME, Howland SW, Wittrup KD.
J Mol Biol. 2010 Aug 6;401(1):84-96. Epub 2010 Jun 9.
PMID: 20540948 [PubMed - indexed for MEDLINE]

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Protein Eng Des Sel 2010 AprA modular IgG-scFv bispecific antibody topology

Orcutt KD, Ackerman ME, Cieslewicz M, Quiroz E, Slusarczyk AL, Frangioni JV, Wittrup KD.
Protein Eng Des Sel. 2010 Apr;23(4):221-8. Epub 2009 Dec 17.
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Biotechnol Prog 2009Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display

Ackerman M, Levary D, Tobon G, Hackel B, Orcutt KD, Wittrup KD.
Biotechnol Prog. 2009 May-Jun;25(3):774-83.
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Mol Cancer Ther 2008Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids

Ackerman ME, Pawlowski D, Wittrup KD.
Mol Cancer Ther. 2008 Jul;7(7):2233-40.
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Cancer Immunol Immunother 2008A33 antigen displays persistent surface expression

Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD.
Cancer Immunol Immunother. 2008 Jul;57(7):1017-27.
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